Hormone Pelleting

Important Billing Information for Pelleting Patients, Please Read

Open Letter From Regeneration PC
Testosterone deficiency in men can cause:

  • Loss of muscle mass
  • Reduced strength
  • Impaired athletic performance
  • Increased muscle pain at lower levels of activity
  • Increased risk of injury with physical labor or exercise due to weakened muscles, tendons & ligaments
  • Reduced sense of well-being
  • Reduced energy
  • Depression, lack of drive
  • Increased abdominal fat
  • Osteoporosis
  • Loss of libido
  • Erectile dysfunction
Symptoms of hormone deficiency in women:

  • Hot flashes, night sweats, clammy skin – most typical and sometimes the earliest symptoms of menopause
  • Irritability, anger
  • Difficulty concentrating
  • Anxiety
  • Depression, sometimes a sense of impending death
  • Impaired memory
  • Insomnia
  • Loss of libido
  • Urinary tract and vaginal infections, due to thinning and atrophy of vaginal tissues- 5x as common after menopause
  • Urinary incontinence
  • Fatigue, lack of energy
  • Weight gain
  • Muscle and joint pains
  • Dry and wrinkled skin
  • Hair loss
  • Lightheadedness
  • Numbness or tingling of the extremities
  • Osteoporosis symptoms: loss of height, spine, hip or wrist fracture

Men & Women: Get Your Body Back in Balance

men-and-women-pelletingMen and women need adequate levels of testosterone for optimal mental and physical health and for the prevention of chronic illnesses like Alzheimer’s and Parkinson’s disease, which are associated with low testosterone levels. Testosterone, delivered by pellet implant, increases lean body mass (muscle strength, bone density) and decreases fat mass even in patients who have failed with other types of hormone therapy.

Data supports that hormone replacement therapy with pellet implants is the most effective and the most bio-identical method to deliver hormones in both men and women. Implants, placed under the skin, consistently release small, physiologic doses of hormones providing optimal therapy. Pellets have been used in both men and women since the late 1930’s.


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Pellets are made up of either estradiol or testosterone. The hormones are pressed or fused into very small solid cylinders. These pellets are larger than a grain of rice and smaller than a breath mint. Pellets deliver consistent, healthy levels of hormones for 3-5 months in women and 4-6 months in men. They avoid the fluctuations, or ups and downs, of hormone levels seen with every other method of delivery. Estrogen delivered by subcutaneous pellets, maintains the normal ratio of estradiol to estrone. This is important for optimal health and disease prevention. Pellets do not increase the risk of blood clots like conventional or synthetic hormone replacement therapy.

In studies, when compared to conventional hormone replacement therapy, pellets have been shown to be superior for relief of menopausal symptoms, maintenance of bone density, restoration of sleep patterns, and improvement in sex drive, libido, sexual response and performance.

Testosterone delivered by a pellet implant, has been used to treat migraine and menstrual headaches. It also helps with vaginal dryness, incontinence, urinary urgency and frequency. In both men and women, testosterone has been shown to increase energy, relieve depression, increase sense of well being, relieve anxiety and improve memory and concentration.

The insertion of pellets is a simple, relatively painless procedure done under local anesthesia. The pellets are usually inserted in the lower abdominal wall or upper buttocks through a small incision, which is then taped closed. The experience of the health care professional matters a great deal, not only in placing the pellets, but also in determining the correct dosage of hormones to be used. Complications from the insertion of pellets include: minor bleeding or bruising, discoloration of the skin, infection, and the possible extrusion of the pellet. Other than slight bruising, or discoloration of the skin, these complications are very rare. Testosterone stimulates the bone marrow and increases the production of red blood cells. A low testosterone level in older men is a cause of anemia. Testosterone, delivered by implants or other methods, can cause an elevation in the red blood cells. If the hemoglobin and hematocrit (blood count) get too high, a unit of blood may be donated.

After the insertion of the implants, vigorous physical activity is avoided for 48 hours in women and up to 5 to 7 days in men. Early physical activity is a cause of ‘extrusion’, which is a pellet working its way out. Antibiotics may be prescribed if a patient is diabetic or has had a joint replaced. However, this is a ‘sterile procedure’ and antibiotics may not be needed.

Some patients begin to ‘feel better’ within 24-48 hours while others may take a week or two to notice a difference. Diet and lifestyle, along with hormone balance are critical for optimal health. Stress is a major contributor to hormone imbalance and illness. Hormone levels will be drawn and evaluated before therapy is started. This will include a FSH, estradiol, testosterone and free testosterone for women. Thyroid hormone levels may also be evaluated. Men need a PSA, sensitive estradiol, testosterone, liver profile and blood count prior to starting therapy. Levels will be reevaluated during hormone therapy, approximately 6 weeks after pellets are inserted and prior to any additional insertions. After the first year of therapy, hormones levels may be followed less frequently. Men must notify their primary care physician and obtain a digital rectal exam each year. Women are advised to continue their monthly self-breast exam and obtain a mammogram and/or pap smear as advised by their gynecologist or primary care physician.

The pellets usually last between 3-5 months in women and 4-6 months in men. The pellets do not need to be removed as they completely dissolve on their own.